李磊
“骏马计划”研究员
办公室：南校区化学楼439
邮箱：leili@imu.edu.cn
教育背景
2009-2013：北京大学药学院，理学学士
2013-2018：北京大学，理学博士（药物化学专业），导师：贾彦兴 教授
工作经历
2018-2019：北京大学药学院，研究助理，合作导师：贾彦兴 教授
2019-2022：美国普渡大学，博士后，合作导师：Mingji Dai教授
2022-2024：美国埃默里大学，博士后，合作导师：Mingji Dai教授
2024-至今：内蒙古大学化学化工学院，“骏马计划”研究员
研究领域
1. 活性天然产物全合成与药物合成；
2. 合成方法学研究；
3. 活性化合物发现与结构改造
发表论文
1. Cai, X.#; Li, L.#; Wang, Y.-C.; Zhou, J.; Dai, M.* Total Syntheses of Phleghenrines A and C. Org. Lett. 2023, 25, 5258–5261. (#These authors contributed equally to this work)
2. Dai, J.#; Yin, X.#; Li, L.#; Rivera, M. E.; Wang, Y.-C.; Dai, M.* Modular and practical diamination of allenes. Nature Communications 2023, 14, 1774. (#These authors contributed equally to this work)
3. Li, L.; Liang, W.; Rivera, M. E.; Wang, Y.-C. Dai, M.* Concise Synthesis of (-)-GA18 Methyl Ester. J. Am. Chem. Soc. 2023, 145, 53-57.
4. Li, K.; Wang, Y.; Chen, L.; Li, L.; Jia, Y.* Synthesis of benzofuro[3,2-b]indolines via regioselective electrooxidative coupling of indoles and phenols. Tetrahedron. Lett. 2021, 63, 152603.
5. Li, L.; Yuan, K.; Jia, Q.; Jia, Y.* Eight-Step Total Synthesis of Phalarine via Bioinspired Oxidative Coupling of Indole and Phenol. Angew. Chem. Int. Ed. 2019, 58, 6074–6078.
6. Li, L.; Chen, Z.; Zhang, X.; Jia, Y.* Divergent Strategy in Natural Product Total Synthesis. Chem. Rev. 2018, 118, 3752-3832.
7. Li, L.; Paruke, A.; Jia, Q.; Jia, Y.* Total Syntheses of Naucleamides A–C and E, Geissoschizine, Geissoschizol, (E)-Isositsirikine, and 16-epi-(E)-Isositsirikine. Org. Let. 2017, 19, 2642–2645.
8. Li, L.#; Yang, Q.#; Wang, Y.; Jia, Y.* Catalytic Asymmetric Total Synthesis of (−)‐Galanthamine and (−)‐Lycoramine. Angew. Chem. Int. Ed. 2015, 54, 6255-6259. (#These authors contributed equally to this work)
9. Li, L.; Hu,W.; Jia, Y.* Synthetic Studies of Cyclic Peptides Stephanotic Acid Methyl Ester, Celogentin C, and Moroidin. Tetrahedron 2014, 70, 7753-7762.
10. Guo, L.; Zhang, F.; Hu, W.; Li, L.; Jia, Y.* Palladium-catalyzed Synthesis of Benzofurans via C–H Activation/Oxidation Tandem Reaction and its Application to the Synthesis of Decursivine and Serotobenine. Chem. Commun. 2014, 50, 3299-3302.
11. Fang, W.; Luo, Z.; Wang, Y.; Zhou, W.; Li, L.; Chen Y.; Zhang, X. Dai, M.; Dai, J.; An SN2 Reaction at Amide Nitrogen Enables Hydrazide Synthesis. Angew. Chem. Int. Ed. 2024, 63, e202317570, doi.org/10.1002/anie.202317570.
12. Luo, Y.; Li, L.; Dai, M. “Complex Natural Products Total Syntheses Facilitated by Palladium-Catalyzed Carbonylative Cyclizations” in “The Chemical Transformations of C1 Compounds”, Volume 2, Chapter 18, 793-826, Book Editors: Kuling Ding, Xiao-Feng Wu, Buxing Han, Zhongmin Liu, Wiley.
13. 贾彦兴; 杨巧; 李磊. 加兰他敏和力克拉敏的不对称合成方法. ZL201410800466.X. 2015-5-6.
